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The following active life science portfolio companies and select exits are, or were, managed by members of the Lightstone team in the healthcare portfolios of Morgenthaler and/or ATV as indicated.

Cala Health
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Cala Health

Cala Health is a medical device company developing novel therapies based on recent neuroscience discoveries from Stanford University.

Lightstone Lead: Mike Carusi
Fund: Lightstone Ventures I
Location: Burlingame, CA
Claret Medical
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Claret Medical

Claret Medical is a developer of innovative solutions for cerebral protection during structural heart, vascular and cardiac surgery procedures.

Lightstone Lead: Hank Plain
Fund: Lightstone Ventures I
Location: Santa Rosa, CA
EarLens
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EarLens

EarLens is developing next generation hearing technology that uses light to transmit sound and energy directly to the eardrum enabling users to appreciate high frequency sounds and improved speech recognition, especially in noisy environments.

Lightstone Lead: Hank Plain
Fund: Lightstone Ventures I
Location: Redwood City, CA
EndoGastric Solutions
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EndoGastric Solutions

Endogastric Solutions is developing an endoscopic medical device that can restore the competency of the anti-reflux barrier, which is distorted in GERD patients and contributes to acid reflux.

Lightstone Lead: Mike Carusi
Legacy Fund: ATV
Location: Redwood City, CA / Redmond, WA
FIRE1
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FIRE1

FIRE1 is a medical device company developing novel remote monitoring devices to improve patient quality of life and outcomes while lowering overall healthcare costs.

Lightstone Lead: Jason Lettmann
Fund: Lightstone Ventures I
Location: Dublin, Ireland
ForSight VISION5
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ForSight VISION5

VISION5 is a medical device company focused on a novel anterior segment drug delivery program for ophthalmic drugs.  The company was incubated within ForSight Labs.

Lightstone Lead: Robin Bellas
Legacy Fund: Morgenthaler
Location: Menlo Park, CA
Holaira
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Holaira

Holaira is a medical device company developing novel devices for treating obstructive lung diseases. The company was incubated within The Foundry.

Lightstone Lead:
Legacy Fund: ATV & Morgenthaler
Location: Minneapolis, MN
Moximed
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Moximed

Moximed is a medical device company that is developing innovative devices for patients with osteoarthritis of the knee.  The company was incubated within the ExploraMed incubator.

Lightstone Lead: Hank Plain
Legacy Fund: Morgenthaler
Location: Hayward, CA
Powervision
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Powervision

PowerVision is developing a proprietary fluid-controlled accommodating intraocular lens (IOL) technology to restore the vision of youth to millions of middle-aged or elderly individuals.

Lightstone Lead: Mike Carusi
Legacy Fund: ATV
Location: Belmont, CA
Relievant Medsystems
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Relievant Medsystems

Relievant is a medical device company developing a new, minimally invasive technology that targets the source of chronic low back pain with a simple one-hour treatment.

Lightstone Lead: Jason Lettmann
Legacy Fund: Morgenthaler
Location: Redwood City, CA
SetPoint Medical
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SetPoint Medical

SetPoint Medical is a medical device company developing a neuromodulation platform for the treatment of debilitating inflammatory diseases, such as Crohn's Disease and Rheumatoid Arthritis. 

Lightstone Lead: Hank Plain
Fund: Morgenthaler
Location: Valencia, CA
Spine Wave
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Spine Wave

Spine Wave is developing and marketing novel devices for spine surgery, specifically spinal fusion, vertebral compression fracture repair, and nucleus replacement and augmentation.

Lightstone Lead:
Legacy Fund: Morgenthaler
Location: Shelton, CT
Vapotherm
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Vapotherm

Vapotherm is a commercial-stage company developing high flow therapy for clinically effective respiratory support.

Lightstone Lead: Jason Lettmann
Fund: Morgenthaler
Location: Exeter, NH
Willow
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Willow

Willow is developing a wearable breast pump that allows women to achieve their breastfeeding goals without pressing pause on their own lives. The company, formerly known as NC7, was incubated within ExploraMed.

Lightstone Lead: Mike Carusi
Fund: Lightstone Ventures I
Location: Mountain View, CA
Altura Medical
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Altura Medical

Altura is a medical device company focused on developing innovative devices and methods for the percutaneous treatment of abdominal aortic aneurysms (AAA). The company was acquired by Lombard Medical in 2015.

 

Acquired by Lombard Medical (NASDAQ: EVAR)

Lightstone Lead: Mike Carusi
Fund: ATV
Location: San Clemente, CA
Ardian
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Ardian

Ardian is a medical device company that developed a first-in-class renal denervation catheter for the treatment of hypertension. The company was incubated within The Foundry and was acquired by Medtronic in 2011. 

Acquired by Medtronic (NYSE: MDT)

Lightstone Lead:
Fund: ATV & Morgenthaler
Location: Mountain View, CA
Cabochon
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Cabochon

Cabochon Aesthetics is a medical device company developing effective, scientific solutions for the aesthetic treatment of cellulite. The company was incubated within The Foundry and was acquired by Ulthera in 2014.

 

Acquired by Ulthera, Inc.

Lightstone Lead: Hank Plain
Fund: Morgenthaler
Location: Menlo Park, CA
ForSight VISION2
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ForSight VISION2

VISION2 developed a proprietary ocular punctal plug drug delivery system. It is non-invasive and capable of delivering a variety of drugs to the eye through controlled release to the tear film. 

Acquired by QLT, Inc. (NASDAQ: QLTI)

Lightstone Lead: Robin Bellas
Legacy Fund: Morgenthaler
Location: Menlo Park, CA
ForSight VISION4
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ForSight VISION4

VISION4 is a medical device company focused on developing novel drug delivery therapies for treatment of retinal diseases.  The company was incubated within ForSight Labs.

Lightstone Lead: Robin Bellas
Fund: Morgenthaler
Location: Menlo Park, CA
GI Dynamics
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GI Dynamics

GI Dynamics is a medical device company developing a device to treat metabolic disease with gastric bypass.  The company had an IPO on the Australian Securities Exchange in 2011.

 ASX: GID

Lightstone Lead: Mike Carusi
Fund: ATV
Location: Lexington, MA
IPC
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IPC

IPC is a leading national physician group practice focused on the delivery of hospital medicine.

NASDAQ: IPCM

Lightstone Lead: Robin Bellas
Legacy Fund: Morgenthaler
Location: North Hollywood, CA
IVS
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IVS

IVS is a medical device company developing a femoral artery closure device using a memory-metal clip to achieve hemostasis at the access site after a catheterization procedure.

Acquired by Abbott (NYSE: ABT)

Lightstone Lead: Robin Bellas
Legacy Fund: Morgenthaler
Location: Sunnyvale, CA
MicroVention
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MicroVention

MicroVention develops and markets innovative neuroendovascular technologies for the treatment of vascular diseases in small vessels.  The company was acquired by Terumo in 2006.

Acquired by Terumo (Tokyo Stock Exchange)

Lightstone Lead: Mike Carusi
Legacy Fund: ATV
Location: Tustin, CA
Miramar Labs
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Miramar Labs

Miramar Labs is developing and marketing a non-invasive, lasting treatment for hyperhydrosis and excessive sweating using microwave energy.  The company was incubated within The Foundry.

 

OTCQB: MRLB

Lightstone Lead: Hank Plain
Fund: Morgenthaler
Location: Sunnyvale, CA
Transcend Medical
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Transcend Medical

Transcend Medical is a medical device company focused on the development of devices for the treatment of glaucoma, the leading cause of adult irreversible blindness.  The company was acquired by Alcon (Novartis) in 2016.

 

Acquired by Alcon (NYSE: NVS)

Lightstone Lead: Robin Bellas
Fund: Morgenthaler
Location: Menlo Park, CA
Twelve
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Twelve

Twelve is a medical device company developing a novel device for the treatment of chronic cardiovascular disease.  The company was incubated within The Foundry and was acquired by Medtronic in 2015.

 

Acquired by Medtronic (NYSE: MDT)

Lightstone Lead: Hank Plain
Fund: Morgenthaler
Location: Menlo Park, CA
ZELTIQ
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ZELTIQ

ZELTIQ is developing and marketing a non-invasive, office-based procedure that uses Cryolipolysis, a proprietary cooling technology, to eliminate fat. ZELTIQ had an IPO in 2011.

NASDAQ: ZLTQ

Lightstone Lead: Jean George
Legacy Fund: ATV
Location: Pleasanton, CA
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